
HBOT for Immune Support in Chronic Illnesses
Chronic illnesses, including autoimmune disorders, often involve both immune dysregulation and inflammation. Conditions like rheumatoid arthritis, lupus, and Crohn’s disease involve an overactive immune response that causes chronic inflammation, leading to pain and tissue damage. HBOT’s ability to reduce inflammation and improve oxygen supply to immune cells makes it a valuable adjunct therapy for managing symptoms of autoimmune conditions.
In autoimmune disorders, the immune system mistakenly attacks healthy tissues, resulting in inflammation and cellular damage. HBOT has shown promise in modulating immune function by reducing the activity of overactive immune cells and supporting immune regulation. Studies have found that HBOT can reduce symptoms and improve the quality of life for patients with autoimmune conditions, likely due to its effects on inflammation and cellular repair.
Additionally, HBOT may improve mitochondrial function, which is often impaired in individuals with chronic illnesses. Healthy mitochondria are essential for immune cell energy and function, allowing the immune system to respond effectively. By enhancing mitochondrial health, HBOT supports immune resilience and may improve overall immune response.
HBOT and Inflammation: Balancing Immune Response
While inflammation is a natural part of the immune response, chronic inflammation can lead to a range of health issues, from autoimmune conditions to cardiovascular disease. HBOT’s anti-inflammatory effects make it a powerful tool for regulating immune function by reducing excessive inflammation and helping the body return to homeostasis.
Research has shown that HBOT reduces pro-inflammatory cytokines, molecules responsible for promoting inflammation. By decreasing these cytokines, HBOT helps to control chronic inflammation without suppressing the immune system’s ability to respond to infections. This balancing effect on inflammation can be beneficial for individuals with chronic inflammatory conditions who need immune support without exacerbating inflammation-related symptoms.

For those Looking to Stay Active, Mobile & Healthy
Start Your Wellness Journey Here
Life's adventures aren't waiting. Call today or fill out the inquiry form below to start your Premier Wellness Experience.
By clicking Contact I agree Bucks County Hyperbarics LLC may contact me by phone or text message including by automated means and prerecorded messages about wellness services, and that I can access real estate services without submitting an online form. I acknowledge that I have read and agree to the Terms of Use and Privacy Notice.
Tips for Supporting Immune Health with HBOT
For those considering HBOT as part of their immune support routine, a few strategies can maximize its effectiveness:
Maintain a Nutrient-Rich Diet
Eating foods high in vitamins A, C, E, and zinc can support immune function and complement HBOT’s benefits. Leafy greens, citrus fruits, and lean proteins are excellent choices for immune support.
Stay Physically Active
Exercise promotes circulation and lymph flow, both of which support immune health. Engaging in regular physical activity can complement HBOT’s effects on immune function.
Manage Stress
Chronic stress can impair immune function by increasing inflammation. Practices like meditation, yoga, or deep breathing exercises can support immune health and improve overall wellness.
Stay Hydrated
Proper hydration is essential for lymphatic function, which plays a role in immune defense. Drinking enough water can enhance the effects of HBOT by supporting cellular hydration and circulation.
Citations
Other References
Goyal A, Chonis T, Cooper JS. Hyperbaric cardiovascular effects. [Updated 2019 Jul 12]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2019 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK482231/
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0065522
M A, Ummer VS, Maiya AG, et al. Low level laser therapy for the patients with painful diabetic peripheral neuropathy – A systematic review, Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 10.1016/j.dsx.2019.07.035, (2019).
Wang EB, Kaur R, Fierro M, et al. Safety and penetration of light into the brain. Photobiomodulation in the Brain, 10.1016/B978-0-12-815305-5.00005-1, (49-66), (2019).
Mitochondrial oxidative phosphorylation defect in the heart of subjects with coronary artery disease. Ait-Aissa K, Blaszak SC, Beutner G, et al. Sci Rep. 2019 May 20; 9(1):7623. Epub 2019 May 20.
Jang S, Lewis TS, Powers C, et al. Elucidating mitochondrial electron transport chain supercomplexes in the heart during ischemia-reperfusion. Antioxid Redox Signal. 2017 Jul 1; 27(1):57-69. Epub 2016 Nov 11
Pahwa R, Jialal I. Chronic inflammation. [Updated 2019 Jun 4]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2019 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK493173/
Alberts B, Johnson A, Lewis J, et al. Molecular biology of the cell. 4th edition. New York: Garland Science; 2002. Electron-Transport Chains and Their Proton Pumps. Available from: https://www.ncbi.nlm.nih.gov/books/NBK26904/
Sharma S, Kelly TK, Jones PA. Epigenetics in cancer. Carcinogenesis. 2010;31(1):27–36. doi:10.1093/carcin/bgp220
Gauldie J. Inflammation and the aging process: devil or angel. Nutr Rev. 2007 Dec; 65(12 Pt 2):S167-9.
Hillary RF, Stevenson AJ, Cox SR, et al. An epigenetic predictor of death captures multi-modal measures of brain health. Mol Psychiatry. 2019 Dec 3; Epub 2019 Dec 3.
Banszerus VL, Vetter VM, Salewsky B, et al. Exploring the relationship of relative telomere length and the epigenetic clock in the lipid cardio cohort. Int J Mol Sci. 2019 Jun 21; 20(12). Epub 2019 Jun 21.
Sullivan J, Mirbahai L, Lord JM. Major trauma and acceleration of the ageing process. Ageing Res Rev. 2018 Dec; 48:32-39. Epub 2018 Oct 11.
Mendelsohn AR, Larrick JW. Epigenetic Drift Is a Determinant of Mammalian Lifespan. Rejuvenation Res. 2017 Oct; 20(5):430-436.
Harch, PG. Hyperbaric oxygen in chronic traumatic brain injury: oxygen, pressure, and gene therapy. Med Gas Res 5, 9 (2015) doi:10.1186/s13618-015-0030-6
General Health
Fife CE, Eckert KA, Carter MJ. An update on the appropriate role for hyperbaric oxygen: indications and evidence. Plast Reconstr Surg. 2016;138(3 Suppl):107S–16S. doi:10.1097/PRS.0000000000002714
Thom SR. Oxidative stress is fundamental to hyperbaric oxygen therapy. J Appl Physiol (1985). 2009;106(3):988–995. doi:10.1152/japplphysiol.91004.2008
Fujita N, Ono M, Tomioka T, et al. Effects of hyperbaric oxygen at 1.25 atmospheres absolute with normal air on macrophage number and infiltration during rat skeletal muscle regeneration. PLoS One. 2014;9(12):e115685. Published 2014 Dec 22. doi:10.1371/journal.pone.0115685
Vadas D, Kalichman L, Hadanny A, et al. Hyperbaric oxygen environment can enhance brain activity and multitasking performance. Front Integr Neurosci. 2017;11:25. Published 2017 Sep 27. doi:10.3389/fnint.2017.00025
Hink J, Jansen E. Are superoxide and/or hydrogen peroxide responsible for some of the beneficial effects of hyperbaric oxygen therapy? Med. Hypotheses, 57 (6) (2001), pp. 764-769.
HBOT Mechanism
Bhutani S, Vishwanath G. Hyperbaric oxygen and wound healing. Indian J Plast Surg. 2012;45(2):316–324. doi:10.4103/0970-0358.101309
Thom SR. Hyperbaric oxygen: its mechanisms and efficacy. Plast Reconstr Surg. 2011;127 Suppl 1(Suppl 1):131S–141S. doi:10.1097/PRS.0b013e3181fbe2bf
Thom SR. Oxidative stress is fundamental to hyperbaric oxygen therapy. J Appl Physiol (1985). 2009;106(3):988–995. doi:10.1152/japplphysiol.91004.2008
Wingelaar TT, Brinkman P, van Ooij PJAM, et al. Markers of Pulmonary Oxygen Toxicity in Hyperbaric Oxygen Therapy Using Exhaled Breath Analysis. Front Physiol. 2019;10:475. Published 2019 Apr 24. doi:10.3389/fphys.2019.00475
A.L. Gill, C.N.A. Bell, Hyperbaric oxygen: its uses, mechanisms of action and outcomes, QJM: An International Journal of Medicine, Volume 97, Issue 7, July 2004, Pages 385–395, https://doi.org/10.1093/qjmed/hch074
